Description
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a well-studied peptide analog that activates the AMP-activated protein kinase (AMPK) pathway, a key regulator of cellular energy homeostasis. Originally developed for cardiovascular research, AICAR has become an important tool in studies exploring endurance, metabolism, and mitochondrial biogenesis.
Mechanism of Action:
AICAR functions by mimicking adenosine monophosphate (AMP) in the body, thereby activating AMPK. Once AMPK is stimulated, cells respond by increasing glucose uptake and fatty acid oxidation while reducing energy-consuming processes. This makes AICAR a unique candidate in research related to exercise physiology, metabolic disorders, and mitochondrial health.
Key Research Areas:
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Endurance & Performance: Investigated for its potential to enhance exercise capacity by improving muscular energy efficiency.
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Metabolic Health: Studied for possible benefits in insulin sensitivity, glucose regulation, and fat metabolism.
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Mitochondrial Biogenesis: Researched for its ability to stimulate new mitochondrial production, supporting energy balance at the cellular level.
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Cardiovascular Research: Explored for protective effects on the heart during ischemic conditions.
Specifications:
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Product: AICAR
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Form: Lyophilized peptide powder
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Purity: ≥ 98% (HPLC tested)
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Unit Size: 50mg vial
Storage Guidelines:
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Store lyophilized peptide at -20°C, protected from light and moisture.
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Reconstituted solution should be kept refrigerated (2–8°C) and used within a limited timeframe.
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Avoid repeated freeze-thaw cycles.
